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Index > Protein center > Abca1(Gene name) > Mouse
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  • Abca1 (Gene name),
  • ATP-binding cassette sub-family A member 1 (Protein name ),  ABCA1_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    Abca1(Abc1);
    Protein name:
    ATP-binding cassette sub-family A member 1;
    Alternative:
    ATP-binding cassette transporter 1(ABC-1;ATP-binding cassette 1);
    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    Interacts with MEGF10.
    Function:
    cAMP-dependent and sulfonylurea-sensitive anion transporter. Key gatekeeper influencing intracellular cholesterol transport.
    Subcellular Location:
    Membrane Multi-pass membrane protein
    Protein Attributes:
    Sequence length:
    2261
    Sequence:
    50:
    MACWPQLRLL | LWKNLTFRRR | QTCQLLLEVA | WPLFIFLILI | SVRLSYPPYE | 
    100:
    QHECHFPNKA | MPSAGTLPWV | QGIICNANNP | CFRYPTPGEA | PGVVGNFNKS | 
    150:
    IVSRLFSDAQ | RLLLYSQRDT | SIKDMHKVLR | MLRQIKHPNS | NLKLQDFLVD | 
    200:
    NETFSGFLQH | NLSLPRSTVD | SLLQANVGLQ | KVFLQGYQLH | LASLCNGSKL | 
    250:
    EEIIQLGDAE | VSALCGLPRK | KLDAAERVLR | YNMDILKPVV | TKLNSTSHLP | 
    300:
    TQHLAEATTV | LLDSLGGLAQ | ELFSTKSWSD | MRQEVMFLTN | VNSSSSSTQI | 
    350:
    YQAVSRIVCG | HPEGGGLKIK | SLNWYEDNNY | KALFGGNNTE | EDVDTFYDNS | 
    400:
    TTPYCNDLMK | NLESSPLSRI | IWKALKPLLV | GKILYTPDTP | ATRQVMAEVN | 
    450:
    KTFQELAVFH | DLEGMWEELS | PQIWTFMENS | QEMDLVRTLL | DSRGNDQFWE | 
    500:
    QKLDGLDWTA | QDIMAFLAKN | PEDVQSPNGS | VYTWREAFNE | TNQAIQTISR | 
    550:
    FMECVNLNKL | EPIPTEVRLI | NKSMELLDER | KFWAGIVFTG | ITPDSVELPH | 
    600:
    HVKYKIRMDI | DNVERTNKIK | DGYWDPGPRA | DPFEDMRYVW | GGFAYLQDVV | 
    650:
    EQAIIRVLTG | SEKKTGVYVQ | QMPYPCYVDD | IFLRVMSRSM | PLFMTLAWIY | 
    700:
    SVAVIIKSIV | YEKEARLKET | MRIMGLDNGI | LWFSWFVSSL | IPLLVSAGLL | 
    750:
    VVILKLGNLL | PYSDPSVVFV | FLSVFAMVTI | LQCFLISTLF | SRANLAAACG | 
    800:
    GIIYFTLYLP | YVLCVAWQDY | VGFSIKIFAS | LLSPVAFGFG | CEYFALFEEQ | 
    850:
    GIGVQWDNLF | ESPVEEDGFN | LTTAVSMMLF | DTFLYGVMTW | YIEAVFPGQY | 
    900:
    GIPRPWYFPC | TKSYWFGEEI | DEKSHPGSSQ | KGVSEICMEE | EPTHLRLGVS | 
    950:
    IQNLVKVYRD | GMKVAVDGLA | LNFYEGQITS | FLGHNGAGKT | TTMSILTGLF | 
    1000:
    PPTSGTAYIL | GKDIRSEMSS | IRQNLGVCPQ | HNVLFDMLTV | EEHIWFYARL | 
    1050:
    KGLSEKHVKA | EMEQMALDVG | LPPSKLKSKT | SQLSGGMQRK | LSVALAFVGG | 
    1100:
    SKVVILDEPT | AGVDPYSRRG | IWELLLKYRQ | GRTIILSTHH | MDEADILGDR | 
    1150:
    IAIISHGKLC | CVGSSLFLKN | QLGTGYYLTL | VKKDVESSLS | SCRNSSSTVS | 
    1200:
    CLKKEDSVSQ | SSSDAGLGSD | HESDTLTIDV | SAISNLIRKH | VSEARLVEDI | 
    1250:
    GHELTYVLPY | EAAKEGAFVE | LFHEIDDRLS | DLGISSYGIS | ETTLEEIFLK | 
    1300:
    VAEESGVDAE | TSDGTLPARR | NRRAFGDKQS | CLHPFTEDDA | VDPNDSDIDP | 
    1350:
    ESRETDLLSG | MDGKGSYQLK | GWKLTQQQFV | ALLWKRLLIA | RRSRKGFFAQ | 
    1400:
    IVLPAVFVCI | ALVFSLIVPP | FGKYPSLELQ | PWMYNEQYTF | VSNDAPEDMG | 
    1450:
    TQELLNALTK | DPGFGTRCME | GNPIPDTPCL | AGEEDWTISP | VPQSIVDLFQ | 
    1500:
    NGNWTMKNPS | PACQCSSDKI | KKMLPVCPPG | AGGLPPPQRK | QKTADILQNL | 
    1550:
    TGRNISDYLV | KTYVQIIAKS | LKNKIWVNEF | RYGGFSLGVS | NSQALPPSHE | 
    1600:
    VNDAIKQMKK | LLKLTKDSSA | DRFLSSLGRF | MAGLDTKNNV | KVWFNNKGWH | 
    1650:
    AISSFLNVIN | NAILRANLQK | GENPSQYGIT | AFNHPLNLTK | QQLSEVALMT | 
    1700:
    TSVDVLVSIC | VIFAMSFVPA | SFVVFLIQER | VSKAKHLQFI | SGVKPVIYWL | 
    1750:
    SNFVWDMCNY | VVPATLVIII | FICFQQKSYV | SSTNLPVLAL | LLLLYGWSIT | 
    1800:
    PLMYPASFVF | KIPSTAYVVL | TSVNLFIGIN | GSVATFVLEL | FTNNKLNDIN | 
    1850:
    DILKSVFLIF | PHFCLGRGLI | DMVKNQAMAD | ALERFGENRF | VSPLSWDLVG | 
    1900:
    RNLFAMAVEG | VVFFLITVLI | QYRFFIRPRP | VKAKLPPLND | EDEDVRRERQ | 
    1950:
    RILDGGGQND | ILEIKELTKI | YRRKRKPAVD | RICIGIPPGE | CFGLLGVNGA | 
    2000:
    GKSTTFKMLT | GDTPVTRGDA | FLNKNSILSN | IHEVHQNMGY | CPQFDAITEL | 
    2050:
    LTGREHVEFF | ALLRGVPEKE | VGKVGEWAIR | KLGLVKYGEK | YASNYSGGNK | 
    2100:
    RKLSTAMALI | GGPPVVFLDE | PTTGMDPKAR | RFLWNCALSI | VKEGRSVVLT | 
    2150:
    SHSMEECEAL | CTRMAIMVNG | RFRCLGSVQH | LKNRFGDGYT | IVVRIAGSNP | 
    2200:
    DLKPVQEFFG | LAFPGSVLKE | KHRNMLQYQL | PSSLSSLARI | FSILSQSKKR | 
    2250:
    LHIEDYSVSQ | TTLDQVFVNF | AKDQSDDDHL | KDLSLHKNQT | VVDVAVLTSF | 
    2261:
    LQDEKVKESY | V
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    KEGG:
    Pfam:
    UniGene:
    String:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse ATP-binding cassette sub-family A member 1
    Cat.:
    E1242h
    Price:
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    MSDS:
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    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Mouse ATP-binding cassette sub-family A member 1
    Cat.:
    E1242m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Mouse ATP-binding cassette sub-family A member 1
    Cat.:
    U1242m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Mouse ATP-binding cassette sub-family A member 1
    Cat.:
    U1242h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    Polyclonal Antibody for Mouse ATP-binding cassette sub-family A member 1
    Cat.:
    P1242Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse ATP-binding cassette sub-family A member 1
    Cat.:
    P1242Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Mouse ATP-binding cassette sub-family A member 1
    Monoclonal Antibody for Mouse ATP-binding cassette sub-family A member 1
    Protein for Mouse ATP-binding cassette sub-family A member 1
    Protein for Mouse ATP-binding cassette sub-family A member 1

    R&D Technical Data
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    Precision
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    Recovery
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    Linearity
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    References
    1. 1.
      "Cloning of two novel ABC transporters mapping on human chromosome 9."
      Luciani M.-F. , Denizot F. , Savary S. , Mattei M.-G. , Chimini G.
      Genomics21:150-159(1994) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      strain: DBA/2.
      tissue: Macrophage.
    2. 2.
      "Human and mouse ABCA1 comparative sequencing and transgenesis studies revealing novel regulatory sequences."
      Qiu Y. , Cavelier L. , Chiu S. , Yang X. , Rubin E. , Cheng J.-F.
      Genomics73:66-76(2001) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
      strain: C57BL/6J.
    3. 3.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
      strain: C57BL/6J.
    4. 4.
      Mural R.J. , Adams M.D. , Myers E.W. , Smith H.O. , Venter J.C.
      Submitted (2005-09) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    5. 5.
      "Bacterial lipopolysaccharide induces expression of ABCA1 but not ABCG1 via an LXR-independent pathway."
      Kaplan R. , Gan X. , Menke J.G. , Wright S.D. , Cai T.-Q.
      J. Lipid Res.43:952-959(2002) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INDUCTION BY LIPOPOLYSACCHARIDE
    6. 6.
      "Endotoxin down-regulates ABCG5 and ABCG8 in mouse liver and ABCA1 and ABCG1 in J774 murine macrophages: differential role of LXR."
      Khovidhunkit W. , Moser A.H. , Shigenaga J.K. , Grunfeld C. , Feingold K.R.
      J. Lipid Res.44:1728-1736(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: DOWN-REGULATION BY ENDOTOXIN
    7. 7.
      "Cooperation between engulfment receptors: the case of ABCA1 and MEGF10."
      Hamon Y. , Trompier D. , Ma Z. , Venegas V. , Pophillat M. , Mignotte V. , Zhou Z. , Chimini G.
      PLoS ONE1:E120-E120(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH MEGF10
    8. 8.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-1296;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Liver.
    9. 9.
      "Mass-spectrometric identification and relative quantification of N-linked cell surface glycoproteins."
      Wollscheid B. , Bausch-Fluck D. , Henderson C. , O'Brien R. , Bibel M. , Schiess R. , Aebersold R. , Watts J.D.
      Nat. Biotechnol.27:378-386(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-489
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